TABLE 2

Summary of Global Lung Function Initiative (GLI) equations for spirometry and current evidence regarding application of these equations in different populations

GLI reference populationGLI data sourcesPopulation/ancestral originConsiderations
WhiteEurope, Israel, Australia, USA, Canada, Brazil, Chile, Mexico, Uruguay, Venezuela, Algeria, TunisiaWhite (European); Hispanic (European)Suitable for use in White European populations [36, 175, 176]
BlackAfrican AmericanBlack (North America)
South East AsianThailand, Taiwan, China (including Hong Kong)Asian
North East AsianJapan, KoreaNorth East Asian equations demonstrate poor fit when applied to contemporary populations [29]
Multi-ethnicAverage of the other four GLI groupsMultiracial; Black South Africa [177]; India [178]; unknownIndian [178] and South African [177] data based on a single prospective study in children