Association of Staphylococcus aureus lineage with death, rash, haemoptysis and leukopenia in 143 adult patients with severe community-acquired pneumonia
| Regression coefficient | ||||
| Death HR (95% CI) | Rash OR (95% CI) | Haemoptysis OR (95% CI) | Leukopenia OR (95% CI) | |
| Charlson comorbidity score | 1.11 (0.95–1.29) | 0.90 (0.61–1.32) | 0.97 (0.78–1.21) | 0.80 (0.62–1.04) |
| CC121 | 1.71 (0.66–4.42) | 24.19 (4.85–120.48) | 0.68 (0.16–2.90) | 0.90 (0.16–4.97) |
| CC152 | 2.55 (1.07–6.09) | 0.47 (0.05–4.61) | 3.30 (0.96–11.29) | 7.84 (2.06–29.81) |
| CC30 | 0.69 (0.25–1.89) | 0.87 (0.15–4.95) | 0.68 (0.21–2.23) | 1.17 (0.31–4.40) |
| CC398 | 1.07 (0.39–2.94) | 0.62 (0.07–5.62) | 1.04 (0.30–3.58) | 4.47 (1.22–16.34) |
| CC5 | 0.38 (0.09–1.66) | ¶ | 0.56 (0.14–2.33) | 0.79 (0.15–4.31) |
| CC8 | 1.03 (0.34–3.11) | ¶ | 0.53 (0.10–2.88) | 2.62 (0.52–13.15) |
| CC80 | 1.59 (0.58–4.35) | 0.94 (0.10–9.13) | 1.39 (0.34–5.68) | 3.47 (0.77–15.58) |
| Charlson comorbidity score# | p=0.54 | p=0.45 | p=0.32 | p=0.02 |
| Lineage# (CC) | p=0.15 | p<0.001 | p=0.35 | p=0.01 |
Lineages with sample size <10 were pooled and used as the reference category. Death prediction model used multivariable Cox regression, with coefficients reported as hazard ratios (HRs). Other models used multivariable logistic regression, with coefficients reported as odds ratios. #: analysis of deviance, Chi-squared test; ¶: unresolved coefficient due to small sample size.