TABLE 1

Potential objectives of RSV surveillance and corresponding surveillance data indicators from sentinel and registry based surveillance

ObjectiveSentinel surveillance (community and hospital)Passive surveillance using RSV laboratory surveillance database
1) Describe seasonality and trends for RSVARI/extended SARI incidence
ARI/extended SARI RSV incidence
RSV laboratory-confirmed cases
2) Measure positivity rates of RSV across different age groups% of RSV among ARI/extended SARI cases% of RSV among tested patients
3) Support the estimation of healthcare burden of RSVProportion of hospitalisations associated with RSV
ARI/extended SARI incidence
ARI/extended SARI RSV incidence
RSV laboratory-confirmed cases
Duration of hospitalisation, etc.
4) Contribute to the overall understanding of the role of RSV in respiratory disease% of RSV among ARI/extended SARI cases
Ratios of RSV positivity compared with other respiratory pathogens
Ratios of RSV detections/cases compared to detections/cases of other pathogens
5) RSV types and genetic diversityGenotypic characterisation
Phenotypic characterisation
Sequence data stored in an RSV dedicated or general (GenBank) sequence database
Existing laboratory databases containing detailed genetic information
6) Platform and baseline to access impact of immunisation programmesVE of RSV ARI/extended SARI
VE of RSV bronchiolitis (hospital only)
RSV incidence before and after implementation (focus on primary target group for vaccination)
If immunisation status is available: VE among different risk groups
RSV incidence before and after implementation (focus on primary target group for vaccination)

RSV: respiratory syncytial virus; ARI: acute respiratory infection; SARI: severe acute respiratory infection; VE: vaccine effectiveness (this term includes the effectiveness of monoclonal antibodies).