GACRS study | CAMP study | p-value | |
Subjects n | 894 | 286 | |
Age years | 9.28±1.86 | 8.90±2.16 | 7.59×10−3 |
Male sex | 528 (59.06) | 193 (67.48) | 0.0134 |
BMI kg·m−2 | 18.45±3.92 | 18.24±3.28 | 0.357 |
Spirometric measures | |||
FEV1 L | 1.80±0.52 | 1.65±0.47 | 1.03×10−5 |
FEV1 % pred | 98.87±16.84 | 92.82±13.40 | 1.17×10−9 |
FEV1/FVC % | 84.36±7.79 | 79.69±8.07 | 2.20×10−16 |
FEV1/FVC % pred | 94.87±8.70 | 90.36±8.94 | 5.36×10−13 |
Bronchodilator response as % of baseline FEV1 | 5.58±10.20 | 10.86±9.49 | 7.50×10−15 |
Log10 dose-response slope from saline | 1.15±0.54 | 0.97±0.47 | 1.92×10−7 |
Blood tests | |||
Total serum IgE IU·mL−1 | 725.26±898.96 | 1084.29±1945.05 | 2.87×10−3 |
Eosinophil count·mm−2 | 553.84±403.93 | 511.96±425.43 | 0.148 |
Positive skin tests to allergens | 3.08±1.82 | 5.56±4.20 | 2.20×10−16 |
Data are presented as mean±sd or n (%), unless otherwise indicated. GACRS: Genetic Epidemiology of Asthma in Costa Rica Study; CAMP: Childhood Asthma Management Program; BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity.