TABLE 4

Model performance

Study cohort
PredictedObserved
C-index (95% CI)0.67 (0.58–0.72)
30-day major bleeding events %
 Low risk3.42.9
 Intermediate risk7.87.3
 High risk43.744.4

BACS score: previous major bleeding (3 points), age >75 years (1 point), cancer (1 point), syncope (1 point). Points are assigned for the presence of each variable. The sum of the variable points produces the total point score (range 0–6). BACS risk staging increased with point totals: low risk (0 points), intermediate risk (1–3 points) or high risk (>3 points).