Pulmonary outcomes three months after hospitalisation
| N | All | ICU admission (n=15) | No ICU admission (n=88) | p | |
| Spirometry | 103 | ||||
| FVC, L | 3.6 (2.1, 6.0) | 3.8 (3.2, 5.1) | 3.6 (3.0, 4.4) | 0.392 | |
| FVC, % of predicted | 94 (76, 121) | 92 (81, 110) | 95 (87, 108) | 0.730 | |
| FVC, z-score | −0.39 (−0.81, 0.37) | −0.58 (−1.34, 0.19) | −0.33 (−0.80, 0.42) | 0.457 | |
| FVC<LLN, n (%) | 7 (7) | 2 (13) | 5 (6) | 0.269 | |
| FEV1, L | 2.8 (2.2, 3.3) | 2.9 (2.5, 3.9) | 2.7 (2.2, 3.2) | 0.119 | |
| FEV1, % of predicted | 92 (84, 106) | 93 (82, 112) | 92 (84, 106) | 0.706 | |
| FEV1, z-score | −0.51 (−1.11, 0.32) | −0.54 (−1.2, 0.67) | −0.50 (−1.11, 0.22) | 0.973 | |
| FEV1<LLN, n (%) | 11 (11) | 2 (13) | 9 (10) | 0.661 | |
| FEV1/FVC, % | 0.77 (0.73, 0.81) | 0.79 (0.76, 0.85) | 0.76 (0.72, 0.81) | 0.049 | |
| Gas diffusion | 102 | ||||
| DLCO, mmol/kPa/min | 6.8 (5.7, 8.8) | 7.9 (5.2, 9.4) | 6.7 (5.7, 8.3) | 0.794 | |
| DLCO, % of predicted | 83 (72, 92) | 83 (66, 86) | 83 (72, 94) | 0.278 | |
| DLCO, z-score | −0.86 (−1.52, −0.06) | −0.74 (−1.04, −0.60) | −0.88 (−1.54, 0.02) | 0.279 | |
| DLCO <LLN, n (%) | 24 (24) | 4 (29) | 20 (23) | 0.735 | |
| DLCO/VA, mmol/kPa/min·L−1 | 1.39 (1.16, 1.54) | 1.34 (1.18, 1.55) | 1.39 (1.16 1.53) | 0.876 | |
| DLCO/VA, % of predicted | 95 (83, 105) | 95 (94, 97) | 96 (95, 98) | 0.899 | |
| DLCO/VA, z-score | −0.28 (−1.13, 0.39) | −0.46 (−0.90, 0.09) | −0.17 (−1.17, 0.41) | 0.915 | |
| Dyspnoea, oxygen saturation and exercise capacity | |||||
| Dyspnoea, mMRC >0, n (%) | 69 | 37 (54) | 5 (42) | 32 (56) | 0.526 |
| Peripheral oxygen saturation at rest, % | 74 | 96 (95–97) | 95 (94, 97) | 96 (95, 98) | 0.283 |
| 6-minute walking distance, m | 73 | 580 (500, 640) | 615 (441, 705) | 588 (500, 640) | 0.540 |
| Chest CT | 100 | ||||
| Ground-glass opacities >10% in at least one zone, n (%) | 25 (25) | 6 (43) | 19 (22) | 0.108 | |
| Parenchymal bands, n (%) | 19 (19) | 5 (36) | 14 (16) | 0.134 | |
Median (25–75th percentile) unless specified otherwise.
CT: computed tomography; DLCO: diffusion capacity of carbon monoxide; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; ICU: intensive care unit; LLN: lower limits of normal; mMRC: modified Medical Research Council Dyspnea Scale; VA: alveolar ventilation capacity.