ParameterTrial 1: effects on gefapixantTrial 2: effects on pitavastatin
GMR (90% CI)
gefapixant + PYR / gefapixant
(n = 12)
GMR (90% CI)
PITA + gefapixant / PITA
(n = 20)
AUC0-inf1.24 (1.19, 1.30)0.97 (0.93, 1.02)
Cmax0.99 (0.90, 1.08)0.98 (0.90, 1.07)
CLr0.70 (0.64, 0.77)