TABLE 1

Comparison of pulmonary embolism (PE)-positive and PE-negative groups

AllPE positivePE negativep-value
Subjects n13532103
Males94 (70)26 (81)68 (66)0.103
Age years64 (54–76)70 (59–77)63 (52–75)0.207
D-dimer µg·L−11600
(1010–3644)
9841
(2921–10 000)
1285
(891–2742)
<0.001
Days since symptom onset8 (5–12)7 (5–14)8 (5–11)0.597
Hospitalisation days5 (4–8)7 (3–11)5 (4–8)0.239
CTPA for clinical deterioration72 (53)17 (53)55 (53)0.979
Disease extent increase compared to previous CT43 (81)5 (50)38 (88)0.009
Disease extent0.146#
 Low <25%19 (14)3 (9)16 (16)
 Moderate 25–50%47 (35)9 (28)38 (37)
 Severe >50%69 (51)20 (63)49 (47)
ICU24 (18)12 (38)12 (12)0.001
Mechanical ventilation18 (13)10 (31)8 (8)0.001

Categorical variables are presented as n (%) and comparisons between the two groups were made using the Chi-squared test. Continuous variables are presented as median (interquartile range) and comparisons between the two groups were made using the Mann–Whitney U-test. Bold indicates statistical significance. CTPA: computed tomography pulmonary angiography; CT: computed tomography; ICU: intensive care unit. : Cochran–Armitage trend test; #: only 53 of the 72 inpatients had a previous CT.