Patient | Patient No.1 | Patient No.2 | Patient No. 3 | |||||||||||
Age/Gender | 55M | 61F | 61M | |||||||||||
Day of illness at OT initiation (SpO2<92% on RA) | 7 | 5 | 3 | |||||||||||
At PP+HFNT initiation | Days of O2 received (Cumulative) | 7 | 12 | 2 | ||||||||||
PF ratio | 84.8 | 160 | 60.6 | |||||||||||
Time interval | Day of illness | 13 | 14 | 15 | 16 | 17 | 18 | 16 | 17 | 18 | 8 | 9 | 10 | 11 |
Day of PP | 1 | 2 | 3 | 4 | 5 | 6 | 1 | 2 | 3 | 1 | 2 | 3 | 4 | |
Oxygen requirement | O2 devices | HFNT | HFNT | HFNT | HFNT | HFNT | iNO2 | HFNT | HFNT | VM | HFNT | HFNT | HFNT | HFNT |
FiO2 (%) | 100 | 40 | 70 | 40 | 40 | 40 | 40 | 40 | 50 | 50 | 60 | 100 | ||
Flow (L·min−1) | 60 | 55 | 60 | 50 | 50 | 4 | 55 | 55 | 12 | 50 | 60 | 70 | 70 | |
Respiratory parameters | SpO2 (%) | 100 | 98 | 92 | 93 | 95 | 98 | 93 | 89 | 94 | 94 | 95 | 94 | 90 |
PF ratio | 114 | 170 | 77 | 158 | 169 | 165 | 133 | 111 | 91 | 49 | ||||
ROX index | 4.2 | 8.8 | 8.2 | 10.1 | 10.3 | 11.3 | 12.9 | 6.5 | 7.8 | 8.5 | 5.2 | 5.5 | 2.9 |
Abbreviations: PP: Prone Positioning; HFNT: Hight Flow Nasal Therapy; OT: Oxygen Therapy; iNO2: Intranasal oxygen; VM: Venturi Mask; PF ratio: PaO2 to FiO2 ratio; ROX index: ratio of SpO2/FiO2 to respiratory rate; Day of illness at OT initiation (SpO2<92% on room air): Total days of symptoms onset before receiving supplemental oxygen (date of receiving supplemental oxygen – date of symptoms onset+one day); Day of illness at PP+HFNT initiation: Total days of illness before PP+HFNT (date of PP+HFNT initiated – date of illness onset+one day); Days of O2 received at PP+HFNT initiation(Cumulative): Duration of patient on supplemental oxygen before PP+HFNT (date of PP+HFNT initiated – date of receiving supplemental oxygen+one day).