OLD | No OLD | p-value | |
Subjects n | 184 | 726 | |
Characteristics | |||
Age years | 61.3±14.3 | 57.1±15.2 | <0.001 |
Male sex | 62.3% | 48.0% | <0.001 |
BMI | 29.2±6.9 | 30.6±6.8 | <0.001 |
Pre-bronchodilator spirometry | |||
FEV1 L | 2.26±0.77 | 2.87±0.81 | <0.001 |
FEV1 % pred | 75.1±15.6 | 95.8±15.3 | <0.001 |
FEV1/FVC ratio | 0.63±0.09 | 0.77±0.06 | <0.001 |
Post-bronchodilator spirometry | |||
FEV1 L | 2.51±0.83 | 2.94±0.83 | <0.001 |
FEV1 % pred | 82.8±17.7 | 98.0±16.2 | <0.001 |
FEV1/FVC ratio | 0.66±0.11 | 0.79±0.06 | <0.001 |
Change in FEV1 post-bronchodilator | 11.6±10.1% | 2.9±4.1% | <0.001 |
SGRQ total score | 40.5±18.5 | 37.0±17.3 | <0.001 |
Diagnostic questionnaires | |||
ASQ score | 8.5±3.6 | 8.7±3.6 | 0.130 |
COPD-DQ score# | 23.4±5.2 | 20.8±5.3 | <0.001 |
Symptom assessment | |||
CAT total score | 18.2±6.9 | 16.7±7.0 | <0.001 |
Smoking status % | |||
Lifetime nonsmokers | 24.5% | 43.4% | <0.001 |
Previous smokers | 40.8% | 37.2% | |
Current smokers | 34.8% | 19.4% | |
Smoking history | |||
Total pack-years in previous and current smokers | 31.4±24.3 | 19.8±18.5 | <0.001 |
Data are presented as mean±sd, unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; SGRQ: St George's Respiratory Questionnaire; ASQ: Asthma Screening Questionnaire; COPD-DQ: COPD-Diagnostic Questionnaire; CAT: COPD Assessment Test. #: 499 subjects completed this questionnaire (116 with OLD and 383 without OLD).