Healthy donors | Severe asthma patients | |
Subjects n | 11 | 31 |
Age years | 38 (24–61) | 57 (19–78) |
Females % | 64 | 58 |
BMI >30 kg·m−2 % | 0 | 47.2 |
ACT >20 % | NA | 17.7 |
Exacerbations in the last year | NA | 4 (0–12) |
FEV1 % predicted | 100 (95–105) | 68 (34–112) |
Blood eosinophils per mm3 | 0 (0–168) | 350 (0–1320) |
Atopy# % | 0 | 35.4 |
Sinusitis % | 0 | 9.5 |
GORD % | 0 | 26.8 |
Long-term OCS % | 0 | 45.2 |
Data are presented as median (range), unless otherwise stated. ACT: asthma control test; FEV1: forced expiratory volume in 1 s; GORD: gastro-oesophageal reflux disease; OCS: oral corticosteroids; NA: nonapplicable. #: based on positive skin test.