TABLE 3

Univariate analysis of mortality risk factors for patients with COVID-19 pneumonia

CharacteristicsDeceasedSurvivorsOR (95%CI)p-value
Patients n21158
Age group years
 0–49031.00.000 (0.000–)0.997
 50–6419.038.62.673 (0.859–8.318)0.090
 ≥6581.030.49.740 (3.113–30.476)<0.001
Underlying diseases
 Hypertension61.928.54.081 (1.584–10.510)0.004
 Cardiovascular or cerebrovascular diseases57.110.811.059 (4.068–30.063)<0.001
Symptoms
 Dyspnoea85.744.97.352 (2.082–25.966)0.002
 Fatigue61.936.72.802(1.096–7.160)0.031
 Sputum production57.127.23.566 (1.403–9.061)0.008
 Headache23.87.63.802 (1.187–12.177)0.025
Respiratory rate >20 breaths·min−147.631.02.022(0.806–5.076)0.134
White blood cells ×109cells·L−1
 >1033.312.73.450 (1.242–9.580)0.017
 4–1052.460.11.371 (0.550–3.418)0.499
 <414.327.20.446 (0.125–1.590)0.213
Neutrophils ×109cells·L−1
 >6.357.124.74.068 (1.594–10.382)0.003
 1.8–6.333.365.20.267 (0.102–0.700)0.071
 <1.89.510.10.934 (0.199–4.384)0.931
Lymphocytes <1.1×109cells·L−190.572.23.667(0.820–16.400)0.089
CD3+CD8+ T-cells ≤75 cells·μL−178.940.05.625 (1.664–19.013)0.005
C-reactive protein ≥10 mg·L−195.287.32.901 (0.368–22.878)0.312
Procalcitonin ≥0.5 ng·mL−121.19.92.438 (0.631–9.414)0.196
Cardiac troponin I ≥0.05 ng·mL−161.517.97.314 (1.832–29.210)0.005
Myoglobin >100 ng·mL−164.318.48.000 (2.157–29.671)0.002
Brain natriuretic peptide >100 pg·mL−194.167.67.680 (0.909–64.906)0.061
Aspartate aminotransferase >40 U·L−147.629.92.134 (0.848–5.373)0.108
Creatinine ≥133 μmol·L−119.02.111.137 (2.296–54.028)0.003
D-dimer ≥0.5 mg·L−176.247.93.474 (1.152–10.481)0.027
PaO2 mmHg
 ≥8014.341.70.233 (0.065–0.840)0.026
 60–7928.632.40.834 (0.298–2.334)0.730
 <6057.125.93.810 (1.451–10.004)0.007
PaO2:FIO2 <200 mmHg47.629.22.204 (0.854–5.684)0.102

Data are presented as %, unless otherwise stated. PaO2: arterial oxygen tension; FIO2: inspiratory oxygen fraction.