TABLE 3

Univariate Analysis of Mortality Risk Factors for Patients with COVID-19 Pneumonia#

CharacteristicDeceased (n=21)Survivors (n=158)OR (95%CI)p value
Age group, %
 0‒49 years031.00.000 (0.000‒)0.997
 50–64 years19.038.62.673(0.859‒8.318)0.090
 ≥65 years81.030.49.740 (3.113‒30.476)<0.001
Underlying diseases, %
 Hypertension61.928.54.081 (1.584‒10.510)0.004
 Cardiovascular or cerebrovascular diseases57.110.811.059 (4.068‒30.063)<0.001
Symptom, %
 Dyspnea85.744.97.352 (2.082‒25.966)0.002
 Fatigue61.936.72.802(1.096‒7.160)0.031
 Sputum production57.127.23.566 (1.403‒9.061)0.008
 Headache23.87.63.802 (1.187‒12.177)0.025
Respiratory rate >20 breath·min−1, %47.631.02.022(0.806‒5.076)0.134
White blood cell counts, %
 >10×109/L33.312.73.450 (1.242‒9.580)0.017
 4‒10×109/L52.460.11.371 (0.550‒3.418)0.499
 <4×109/L14.327.20.446 (0.125‒1.590)0.213
Neutrophil counts, %
 >6.3×109/L57.124.74.068 (1.594‒10.382)0.003
 1.8‒6.3×109/L33.365.20.267 (0.102‒0.700)0.071
 <1.8×109/L9.510.10.934 (0.199‒4.384)0.931
Lymphocyte counts <1.1× 109/L, %90.572.23.667(0.820–16.400)0.089
CD3+CD8+ T cells ≤75 cell·μL−1, %78.940.05.625 (1.664–19.013)0.005
C-response protein ≥10 mg·L−1, %95.287.32.901 (0.368‒22.878)0.312
Procalcitonin ≥0.5 ng·mL−1, %21.19.92.438 (0.631‒9.414)0.196
Cardiac troponin I≥0.05 ng·mL−1, %61.517.97.314 (1.832‒29.210)0.005
Myoglobin >100 ng·mL−1, %64.318.48.000 (2.157‒29.671)0.002
Brain natriuretic peptide >100 pg·mL−1, %94.167.67.680 (0.909‒64.906)0.061
Aspartate aminotransferase >40 U·L−1, %47.629.92.134 (0.848‒5.373)0.108
Creatinine ≥133 μmol·L−1, %19.02.111.137 (2.296‒54.028)0.003
D-dimer ≥0.5 mg·L−1, %76.247.93.474 (1.152‒10.481)0.027
PaO2, %
 ≥80 mmHg14.341.70.233 (0.065‒0.840)0.026
 60‒79 mmHg28.632.40.834 (0.298‒2.334)0.730
 <60 mmHg57.125.93.810 (1.451‒10.004)0.007
 PaO2:FIO2<200 mmHg47.629.22.204 (0.854‒5.684)0.102

CI: confidence interval; OR: odd ratio; PaO2: Arterial partial pressure of oxygen; FIO2: fraction of inspiration O2.

#Data are reported as median interquartile (IQR).