TABLE 4

Comparisons of Multidimensional Dyspnea Profile (MDP) in hyperinflator and non-hyperinflator pulmonary hypertension patients

HyperinflatorNon-hyperinflatorp-value
Subjects n179
6MWT
 Borg at 6 min4.7±3.15.6±2.80.47
MDP
 A1 scale
  Unpleasantness or discomfort#3.8±2.94.9±2.90.37
  My breathing requires muscle work or effort22220.10
  I am not getting enough air or I am smothering or I feel hunger for air4500.025
  My chest and lungs feel tight or constricted11220.47
  My breathing requires mental effort or concentration0110.08
  I am breathing a lot11450.025
  No response1100.08
 Score S of MDP17±1620±130.45
 A2 scales#
  Depressed0 (0–0)0 (0–0)0.65
  Anxious0 (0–0)0 (0–2)0.29
  Frustrated0 (0–0)0 (0–0)0.81
  Angry0 (0–0)0 (0–0)0.36
  Afraid0 (0–0)0 (0–0)0.52
  Other?0 (0–0)0 (0–0)1
 Score A2 of MDP0 (0–0)2 (0–5)0.10
CPET
 Borg at peak7.2±1.66.4±1.40.11
 MDP
 A1 scale
  Unpleasantness or discomfort#8 (7–9)5 (0–8)0.037
  My breathing requires muscle work or effort000.81
  I am not getting enough air or I am smothering or I feel hunger for air65110.025
  My chest and lungs feel tight or constricted0110.08
  My breathing requires mental effort or concentration0110.08
  I am breathing a lot29560.037
  No response6110.10
 Score S of MDP29±1326±120.56
 A2 scales#
  Depressed0 (0–0)0 (0–0)0.78
  Anxious0 (0–4)0 (0–2)0.3
  Frustrated0 (0–2)0 (0–4)0.93
  Angry0 (0–0)0 (0–0)0.8
  Afraid0 (0–1)0 (0–0)0.33
  Other?0 (0–0)0 (0–0)1
 Score A2 of MDP3 (0–7)0 (0–2)0.35
RHC
 Borg at peak7.7±1.96.8±1.60.11
 MDP
 A1 scale
  Unpleasantness or discomfort#6.0±2.85.1±1.80.43
  My breathing requires muscle work or effort12220.63
  I am not getting enough air or I am smothering or I feel hunger for air47220.040
  My chest and lungs feel tight or constricted0110.80
  My breathing requires mental effort or concentration001
  I am breathing a lot35450.43
  No response600.78
 Score S of MDP24±1421±120.71
 A2 scales#
  Depressed0 (0–0)0 (0–0)0.61
  Anxious0 (0–4)0 (0–0)0.37
  Frustrated0 (0–1)0 (0–0)0.65
  Angry0 (0–0)0 (0–0)0.82
  Afraid0 (0–3)0 (0–0)0.35
  Other?0 (0–0)0 (0–0)1
 Score A2 of MDP2 (0–6)0 (0–0)0.22

Data are presented as mean±sd, % or median (interquartile range), unless otherwise stated. Bold type represents statistical significance. 6MWT: 6-min walk test; a.u.: arbitrary units; CPET: cardiopulmonary exercise testing; RHC: right heart catheterisation. #: 0–10 a.u.