Variables | Hazard ratio (95% CI) | p-value |
Univariate analysis | ||
Age years | 1.031 (0.998–1.066) | 0.07 |
Males | 1.221 (0.570–2.614) | 0.61 |
Weight kg | 0.980 (0.948–1.014) | 0.24 |
Age at admission <50 years | 0.427 (0.146–1.248) | 0.12 |
HIV infection | 1.043 (0.504–2.158) | 0.91 |
Previous TB treatment | 1.195 (0.579–2.466) | 0.63 |
Previous treatment failures | 1.304 (0.536–3.173) | 0.56 |
Days of admission | 1.002 (1.000–1.004) | 0.06 |
Clofazimine treatment | 0.731 (0.220–2.426) | 0.61 |
Delamanid treatment | 3.668 (1.712–7.859) | 0.001 |
Moxifloxacin treatment | 1.306 (0.619–2.757) | 0.48 |
Levofloxacin treatment | 1.564 (0.748–3.271) | 0.24 |
Linezolid treatment | 0.605 (0.244–1.501) | 0.28 |
Number of medications | 1.104 (0.884–1.380) | 0.38 |
Number of adverse events | 0.976 (0.832–1.145) | 0.77 |
Five likely effective drugs | 2.025 (0.761–5.386) | 0.16 |
TTP <7 days | 0.777 (0.184–3.282) | 0.73 |
SMG >2 pluses | 1.504 (0.609–3.714) | 0.38 |
Multivariate analysis | ||
Five likely effective drugs | 3.167 (0.995–10.08) | 0.05 |
Age years | 1.039 (1.000–1.078) | 0.04 |
Delamanid treatment | 3.504 (1.544–7.954) | 0.003 |
Linezolid treatment | 0.539 (0.200–1.454) | 0.22 |
Levofloxacin treatment | 1.357 (0.494–3.730) | 0.55 |
Days of admission | 1.001 (0.998–1.004) | 0.46 |
Weight kg | 0.975 (0.937–1.015) | 0.23 |
QTc: corrected QT interval; TB: tuberculosis; TTP: time to culture positivity; SMG: sputum smear grade.