TABLE 3

Risk of an exacerbation within 21 days of a URTI with the presence of a certain detected virus at the time of the URTI (total observations: 391)

Risk factor#,¶ValueEstimateStandard errorStandard error ratioHR (95% CI)p-value
Coronavirus 229ENo viral infection0.1350.2901.0841.145 (0.65–2.02)0.641
Coronavirus 229E−0.5291.0331.0150.589 (0.08–4.46)0.608
Coronavirus HKU1No viral infection0.1690.2901.0741.184 (0.67–2.09)0.561
Coronavirus HKU10.1650.7871.0681.179 (0.25–5.51)0.834
Coronavirus NL63No viral infection0.2170.3081.1331.243 (0.68–2.28)0.481
Coronavirus NL630.8920.6661.0632.440 (0.66–9.00)0.180
Coronavirus OC43No viral infection0.1820.2961.0851.199 (0.67–2.14)0.539
Coronavirus OC430.2570.6401.0461.293 (0.37–4.53)0.688
Influenza BNo viral infection0.2020.2861.0581.224 (0.70–2.14)0.480
Influenza B1.0060.8391.1282.734 (0.53–14.10)0.231
MetapneumovirusNo viral infection0.1810.2901.0831.198 (0.68–2.12)0.533
Metapneumovirus1.0390.8890.8652.827 (0.49–16.10)0.242
Parainfluenza 1No viral infection0.2070.2911.0761.231 (0.70–2.18)0.475
Parainfluenza 11.2310.8671.1793.426 (0.63–18.70)0.155
Parainfluenza 3No viral infection0.2780.2891.0501.320 (0.75–2.33)0.336
Parainfluenza 31.8310.6201.1476.238 (1.85–21.00)0.003
RSV ANo viral infection0.1640.2891.0811.178 (0.67–2.08)0.571
RSV A0.1721.0200.9941.187 (0.16–8.76)0.866
RSV BNo viral infection0.1900.2821.0461.210 (0.70–2.10)0.500
RSV B0.6250.7941.0811.869 (0.39–8.86)0.431
Rhino/enterovirusNo viral infection−0.1290.3361.1220.879 (0.45–1.70)0.701
Rhino/enterovirus−0.6470.4371.1530.524 (0.22–1.23)0.139

URTI: upper respiratory tract infection; HR: hazard ratio; RSV: respiratory syncytial virus. #: regressions for which the risk factor was adenovirus, bocavirus, influenza A H1N1, influenza H1 subtype, influenza H3 subtype, parainfluenza 2 and parainfluenza 3 did not converge due to few or no detections; : in all cases, the reference was other viruses detected.