TABLEĀ 2

Main cause of death of patients with concomitant tuberculosis (TB)

GroupHIV statusCDA A diagnosisInfectious agent identifiedType of TB (organs affected)
1ChildrenNegativeRabiesRabies virusPulmonary
2ChildrenNegativePeritonitisUnspecifiedPulmonary
3ChildrenNegativeMalignant brain tumourPulmonary
4ChildrenPositiveSepsisStreptococcus pneumoniaePulmonary
5ChildrenNegativeMeningoencephalitisCryptococcus gattiiExtrapulmonary (CNS)
6ChildrenPositiveMeningitisStreptococcus pneumoniaePulmonary
7ChildrenPositivePneumocystosisPneumocystis jiroveciiExtrapulmonary (CNS)
8ChildrenNegativeSepsisStreptococcus pneumoniaePulmonary
9Maternal deathsPositiveMeningoencephalitisCryptococcus neoformansExtrapulmonary (spleen)
10Maternal deathsPositiveSeptic abortionMycoplasma hominisPulmonary (miliary, both lungs)
11Maternal deathsPositiveEncephalitisUnspecifiedPulmonary
12Maternal deathsPositivePuerperal sepsisPulmonary
13Maternal deathsNegativePneumoniaUnspecifiedPulmonary
14Other adultsnegativeMucormycosisRhizopus oryzaeExtrapulmonary (CNS)
15Other adultsPositiveDiffuse large B-cell lymphomaPulmonary
16Other adultsPositiveIntracerebral haemorrhagePulmonary
17Other adultsPositiveSepsisStreptococcus dysgalactiaePulmonary
18Other adultsPositivePneumoniaKlebsiella pneumoniaeDisseminated (liver lung)
19Other adultsPositiveDiffuse large B-cell lymphomaPulmonary
20Other adultsNegativeMeningitisHerpes simplex virus type 1Pulmonary
21Other adultsPositiveSepsisEscherichia coliPulmonary
22Other adultsNegativeSepsisCandida glabrataPulmonary
23Other adultsPositiveDisseminated Kaposi's sarcomaHuman herpesvirus 8Pulmonary
24Other adultsNegativeSepsisEnterobacter spp.Pulmonary
25Other adultsPositivePneumoniaPseudomonas aeruginosaDisseminated (lung, CNS)
26Other adultsPositiveToxoplasmosisToxoplasma gondiiDisseminated (lung, liver, spleen)
27Other adultsNegativeCardiac arrestPulmonary
28Other adultsPositiveToxoplasmosisToxoplasma gondiiPulmonary
29Other adultsPositiveSepsisLegionella pneumophilaDisseminated (spleen, lung)
30Other adultsPositiveMeningitisStreptococcus pneumoniaeDisseminated (lung, CNS)
31Other adultsPositivePneumoniaUnspecifiedPulmonary

n=31. CDA: complete diagnostic autopsy; CNS: central nervous system.