TABLE 2

Histological measures of the two cohorts

All subjectsCohort for 3D reconstructionCohort for 2D analysis
Subjects371819
Estimated proportion of lung structures
 Alveolar space %81 (8.8)83 (6.1)80 (11)
 Alveolar septa %14 (6.8)14 (5.6)14 (6.1)
 Vessels %4.2 (2.8)4.1 (1.4)4.4 (4.2)
 Bronchi %0.5 (0.7)0.5 (0.7)0.0 (0.7)
Cross-sectional area of vessels <500 µm diameter % total area6.3 (2.2)6.3 (1.7)6.1 (3.1)
Morphometry of pulmonary muscular arteries
 External diameter μm277 (96.0)266 (93.7)278 (97.5)
 Lumen % vessel area41 (16)41 (9)41 (18)
 Intima % vessel area30 (11)31 (12)28 (10)
 Muscularis % vessel area24 (7)25 (6)23 (9)

Data are presented as n or median (interquartile range). 3D: three-dimensional; 2D: two-dimensional.