TABLE 1

Patient characteristics of mild and severe asthma patients and healthy controls

HealthyMild asthmaSevere asthma
Subjects174316
Age years22.26 (19–31)21.36 (18–29)44.53 (25–66)
Sex ratio male:female0.130.470.44
FEV1 pre-bronchodilator L4.17±0.704.10±0.692.72±0.72
FEV1 post-bronchodilator L4.29±0.694.20±0.772.99±0.73
FEV1 pre-bronchodilator % pred108.2±10.51101.12±11.5986.61±21.29
FEV1 post-bronchodilator % pred111.6±10.58107.96±11.6794.76±21.43
FEV1 reversibility3.4±2.606.84±4.478.23±4.91
PC20 mg·mL−1>16.02.57±2.31.42±1.64
FeNO ppb20.8±11.0952.34±30.1561.79±71.02

Data are presented as n, mean (range) or mean±sd. FEV1: forced expiratory volume in 1 s; PC20 provocative concentration causing a 20% fall in FEV1; FeNO: exhaled nitric oxide fraction.