Unit costs

Unit cost EURSource
Study medications, per dose
 Alteplase 10 mg164British National Formulary
 Pulmozyme 2.5 mg19British National Formulary
Initial hospital stays, per day
 Initial stay, nonsurgery502NHS Reference Costs
 Initial stay, surgery955NHS Reference Costs
Subsequent admissions
 Hospital stay#756#NHS Reference Costs

Individual hospitalisation costs were applied in the main analysis. Based on the British National Formulary ( and NHS Reference Costs [21]. #: weighted average for the 37 different reasons patients were readmitted during study follow-up.