TABLE 3

Unweighted and inverse-probability treatment weighting (IPTW) multivariable regression effects of broad-spectrum antibiotics on secondary outcomes

OutcomeUnweighted regression
eβ (95% CI)#
p-valueIPTW-ATT
eβ (95% CI)#
p-value
Length of stay1.66 (1.53–1.8)<0.0011.52 (1.41–1.63)<0.001
Cost1.83 (1.68–2.01)<0.0011.7 (1.57–1.84)<0.001
Clostridioides difficile infection3.85 (1.55–10.93)0.0065.79 (1.86–27.51)0.008

ATT: average treatment effects on the treated. #: exponentiated β coefficients (eβ) are interpreted as multipliers for Γ-distributed variables (length of stay and cost) and as odds ratios for binary outcomes (C. difficile infection).