TABLE 1

Baseline characteristics of the treated cohorts

SurgerySABRCFRTp-value
Subjects3169953
Age years69.9 (57.12–82.7)76.7 (63.5–90.0)76.5 (63.8–89.3)
Age group years
 30–5947 (14.87)4 (4.04)0 (0.00)<0.001
 60–69112 (35.44)21 (21.21)12 (22.64)
 70–79127 (40.19)42 (42.42)20 (37.74)
 ≥8030 (9.49)32 (32.32)21 (39.62)
Female176 (55.70)44 (44.44)30 (56.60)0.050
Histology
 Squamous cell95 (30.06)21 (21.21)16 (30.19)<0.001
 Other215 (68.04)35 (35.35)17 (32.08)
 Benign5 (1.58)0 (0.00)0 (0.00)
 Unknown1 (0.32)43 (43.43)20 (37.74)
Pre-operative stage
 IA197 (62.34)68 (68.69)23 (43.40)0.252
Post-operative stage
 IA140 (44.30)
 IB107 (33.86)
 IIA36 (11.39)
 IIB17 (5.38)
 IIIA9 (2.85)
 IIIB1 (0.32)
 IV1 (0.32)
 Benign5 (1.58)
WHO performance status
 0–1263 (83.23)41 (41.41)17 (32.08)<0.001
 245 (14.24)29 (29.29)20 (37.74)
 3–48 (2.53)29 (29.29)16 (30.19)
Year
 200855 (17.41)0 (0.00)9 (16.98)<0.001
 200951 (16.14)8 (8.08)6 (11.32)
 201046 (14.56)19 (19.19)13 (24.53)
 201154 (17.09)30 (30.30)7 (13.21)
 201272 (22.78)28 (28.28)14 (26.42)
 201338 (12.03)14 (14.14)4 (7.55)

Data are presented as n, median (interquartile range) or n (%), unless otherwise stated. SABR: stereotactic ablative body radiotherapy; CFRT: conventionally fractionated radiotherapy; WHO: World Health Organization. Histological subtype was not significantly different between the cohorts when those without histological confirmation were excluded (p=0.379). p-values represent the comparison between surgery and SABR.