Association between inhaled corticosteroid (ICS) use and lung cancer, using five different definitions of exposure, adjusted for age and sex only
| Exposure metrics | Bivariate hazard ratio (95% CI) | Age- and sex-adjusted hazard ratio (95% CI) |
| Time-dependent ICS exposure | 0.70 (0.61–0.80) | 0.72 (0.63–0.83) |
| Cumulative duration# | 0.89 (0.84–0.95) | 0.90 (0.84–0.96) |
| Cumulative dose# | 0.79 (0.66–0.95) | 0.80 (0.67–0.95) |
| Recency-weighted duration of use | 0.75 (0.68–0.82) | 0.76 (0.68–0.83) |
| Recency-weighted cumulative dose | 0.62 (0.48–0.80) | 0.62 (0.49–0.80) |
#: measured as a continuous variable.