TABLE 2

Clinical and haemodynamic data before and after balloon pulmonary angioplasty

VariablesTotal (n=154)Initial period (n=75)Recent period (n=79)p-value#
Beforep-valueAfterBeforep-valueAfterBeforep-valueAfter
Characteristics
 NYHA FC % (I,II/III,IV)35.3/64.7<0.00178.7/21.325.3/74.7<0.00165.3/34.744.9/55.1<0.00192.0/8.0<0.001
 6MWD m396±120<0.001441±104383±137<0.001434±119407±103<0.001449±860.411
PaO2 mmHg65.0±9.0<0.00173.3±12.065.0±9.90.00173.2±12.965.1±7.90.00873.6±10.50.901
Haemodynamics
 Systolic PAP mmHg75.7±17.0<0.00153.0±16.975.4±16.9<0.00157.4±18.275.9±17.2<0.00148.9±14.70.002
 Diastolic PAP mmHg24.2±7.0<0.00118.4±6.424.6±7.4<0.00120.0±6.823.9±6.6<0.00117.0±5.60.003
 Mean PAP mmHg43.9±9.5<0.00131.6±9.044.3±9.8<0.00133.8±9.843.6±9.1<0.00129.5±7.70.003
 Mean RAP mmHg8.1±3.8<0.0016.3±2.88.0±3.70.0106.6±2.98.2±3.8<0.0016.0±2.70.149
 PAWP mmHg9.6±3.40.05010.3±3.59.8±3.50.17610.4±3.89.4±3.20.16010.1±3.30.524
 Cardiac output L·min−14.86±1.22<0.0015.56±1.354.88±1.27<0.0015.47±1.474.85±1.18<0.0015.65±1.230.400
 Cardiac index L·min−1·m−22.68±0.60<0.0013.07±0.752.62±0.58<0.0012.96±0.802.73±0.62<0.0013.18±0.680.062
 PVR dyn·s·cm−5604±226<0.001329±177607±218<0.001371±188601±236<0.001289±1570.004
SvO2 %62.6±7.4<0.00167.9±7.362.9±7.5<0.00167.3±8.162.4±7.3<0.00168.5±6.40.353
 Absolute change of mean  PAP mmHg−12.4±10.6−10.5±10.4−14.1±10.50.038
 Decrease of mean PAP %−26.1±21.3−21.9±21.5−30.1±20.40.017
 Decrease of PVR %−42.7±27.4−36.5±29.1−48.6±24.50.006

Data are presented as mean±sd, unless otherwise stated. NYHA FC: New York Heart Association functional class; 6MWD: 6-min walk distance; PaO2: arterial partial pressure of oxygen; PAP: pulmonary artery pressure; RAP: right atrial pressure; PAWP: pulmonary artery wedge pressure; PVR: pulmonary vascular resistance; SvO2: mixed venous oxygen saturation. #: comparison between initial and recent periods.