Key treatable traits research questions
| Question | Methodology |
| How should we define individual traits? | Delphi process/consensus statement |
| What is the prevalence of the different traits? | Existing datasets, supplemented by prospective data collection where necessary |
| Which treatable traits matter? | Existing cross-sectional and longitudinal datasets for quality of life, control and future risk |
| Is a broad or narrow/focused approach to managing treatable traits preferable? | Prospective randomised controlled trial, three arms with stratification by baseline diagnosis asthma/chronic obstructive pulmonary disease: guideline based; broad approach at baseline; focused approach at baseline |
| What is the best treatment for specific traits? | Master protocol randomised controlled trials |
| How best to implement treatable traits? | Implementation studies: dynamic control panel embedded in electronic record |