TABLE 1

T-helper cell subsets in CD4+ cells in steroid-treated mice

Control groupTDI groupTDI+prednisone groupTDI+fluticasone propionate group
BALF
 CD4 IFN-γ+ %2.02±0.464.60±0.65**4.32±0.654.34±1.19
 CD4 IL-4+ %0.09±0.082.61±0.67**2.80±0.682.73±0.52
 CD4 IL-17A+ %2.43±0.257.88±1.08**8.24±0.927.93±1.46
Lung
 CD4 IFN-γ+ %0.20±0.070.97±0.21**1.05±0.240.91±0.38
 CD4 IL-4+ %0.11±0.020.61±0.10**0.69±0.210.91±0.16
 CD4 IL-17A+ %0.73±0.101.99±0.39**1.79±0.251.84±0.43

Data are presented as mean±sd. TDI: toluene diisocyanate; BALF: bronchoalveolar lavage fluid; IFN: interferon; IL: interleukin. **: p<0.01, compared with the control group. No significant differences were observed between the TDI group and the TDI+prednisone group or between the TDI group and the TDI+fluticasone propionate group.