TABLE 1

Clinical characteristics of patients in the primary and validation cohorts

Primary cohortp-valueValidation cohortp-value
EGFR-wild typeEGFR-mutantEGFR-wild typeEGFR-mutant
Subjects n603241
Age years59.50±9.7261.36±8.960.01659.59±8.8359.21±7.280.716
Sex<0.001<0.001
 Female99 (39.76)206 (58.19)52 (42.62)79 (66.39)
 Male150 (60.24)148 (41.81)70 (57.38)40 (33.61)
Stage0.0470.017
 I181 (72.69)240 (67.80)50 (40.98)65 (54.62)
 II27 (10.84)27 (7.63)22 (18.03)8 (6.72)
 III36 (14.46)69 (19.49)43 (35.25)35 (29.41)
 IV5 (2.01)18 (5.08)7 (5.74)11 (9.24)
EGFR mutation249 (41.29)354 (58.71)122 (50.62)119 (49.38)

Data are presented as mean±sd, or n (%), unless otherwise stated. EGFR: epidermal growth factor receptor.