TABLE 3

Total cost of bronchiectasis and costs separated by main cost types compared with matched control patients after adjusting for age, sex and Charlson Comorbidity Index scores

Control group without bronchiectasis¶¶Incident bronchiectasis patients++Ratio of the mean (95% CI)p-value§§
SumMeanƒƒ (95% CI)SumMeanƒƒ (95% CI)
Outpatient diagnostic and visiting costs#1 840 235.712792.47 (2699.33–2885.61)632 567.172983.81 (2795.81–3171.81)1.07 (0.995–1.15)0.27ns
Costs of remedies,+158 094.73239.9 (215.44–264.36)82 556.87389.42 (301.68–477.16)1.62 (1.27–2.08)0.02
Medical aids costs¶,§259 848.97394.31 (300.36–488.26)230 186.301085.78 (809.87–1361.69)2.75 (1.95–3.90)<0.001
Sick-pay costsƒ14 603.9822.16 (16.33–27.19)4586.8921.64 (12.63–30.65)0.98 (0.60–1.60)0.8ns
Hospitalisation costs2 757 026.844183.65 (3577.8–4789.5)1 378 925.536504.37 (5098.02–7909.82)1.56 (1.20–3.01)<0.001
Drug costs¶,##4 352 366.436604.5 (3757.13–9451.87)1 621 706.537694.56 (5354.77–9944.35)1.16 (0.69–1.95)0.67ns
Costs of antiobstructive medication704 490.031069.03 (917.46–1136.46)338 229.901595.42 (1444.88–2048.6)1.49 (1.37–1.52)<0.001
Costs of antibiotics56 691.6985.31 (77.80–92.82)87 727.50413.81 (176.28–651.34)4.85 (2.72–8.64)<0.001
Costs of mucoactive agents9322.7314.15 (10.51–16.79)14 863.8170.11 (51.65–88.57)4.96 (4.91–5.28)0.001
Total cost9 382 176.6614 236.99 (11 318.87–17 155.21)3 950 529.2918 634.57 (15 891.02–23 871.13)1.31 (1.02–1.68)<0.001

Data are presented as EUR, unless otherwise stated. #: outpatient costs comprise reimbursement for outpatient physician's office visits, laboratory diagnostics and imaging; : as outpatients; +: remedies comprise physiotherapy treatments and modalities such as active cycle of breathing and postural drainage techniques; §: medical aids comprise nebulisers and respiration therapy equipment; ƒ: sick pay is paid out in the statutory company health insurance as a substitute wage from day 43 of the sick leave according to Section 44 of the 5th German Social Code (SGB V; www.sozialgesetzbuch-sgb.de); ##: prescribed pharmaceuticals according to German national drug (Anatomical Therapeutic Chemical) codes; ¶¶: n=685; ++: n=231; §§: Wilcoxon–Mann–Whitney test (two-sided); ƒƒ: adjusted to patients who died during the observation period. ns: nonsignificant.