Factors related to sentinel lymph node metastasis in patients with melanoma and obstructive sleep apnoea
| Bivariate logistic regression analysis | Stepwise multivariate logistic regression analysis | |||
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Male | 1.358 (0.616–2.987) | 0.450 | ||
| Age years | 0.988 (0.968–0.999) | 0.049 | 0.939 (0.897–0.982) | 0.006 |
| BMI kg·m−2 | 1.003 (0.938–1.073) | 0.949 | ||
| Current smoker | 0.938 (0.395–2.228) | 0.884 | ||
| ESS | 1.011 (0.909–1.123) | 0.845 | ||
| AHI events·h−1 | 1.009 (0.989–1.031) | 0.376 | ||
| ODI events·h−1 | 1.013 (0.996–1.029) | 0.130 | ||
| Mean nocturnal SpO2 % | 1.158 (0.932–1.439) | 0.184 | ||
| Low nocturnal SpO2 % | 0.990 (0.957–1.025) | 0.581 | ||
| tsat90 % | 0.983 (0.949–1.019) | 0.345 | ||
| Mitotic index cells·mm−2 | 1.155 (1.074–1.241) | <0.001 | ||
| Breslow index mm | 1.479 (1.270–1.723) | <0.001 | 1.371 (1.041–1.805) | 0.025 |
| Presence of ulceration | 5.909 (2.646–13.196) | <0.001 | ||
| Clark level | 4.961 (2.690–9.152) | <0.001 | 3.286 (1.155–9.346) | 0.026 |
| Serum sPD-L1 pg·mL−1 | 1.009 (1.004–1.014) | 0.001 | 1.009 (1.002–1.016) | 0.008 |
BMI: body mass index; ESS: Epworth sleepiness score; AHI: apnoea–hypopnoea index; ODI: oxygen desaturation index; SpO2: arterial oxygen saturation measured by pulse oximetry; tsat90: time spent at night with SpO2 <90%; sPD-L1: soluble programmed cell death ligand-1.