TABLE 1

Haemodynamic definitions of pulmonary hypertension (PH)

DefinitionsCharacteristicsClinical groups#
Pre-capillary PHmPAP >20 mmHg1, 3, 4 and 5
PAWP ≤15 mmHg
PVR ≥3 WU
Isolated post-capillary PH (IpcPH)mPAP >20 mmHg2 and 5
PAWP >15 mmHg
PVR <3 WU
Combined pre- and post-capillary PH (CpcPH)mPAP >20 mmHg2 and 5
PAWP >15 mmHg
PVR ≥3 WU

mPAP: mean pulmonary arterial pressure; PAWP: pulmonary arterial wedge pressure; PVR: pulmonary vascular resistance; WU: Wood Units. #: group 1: PAH; group 2: PH due to left heart disease; group 3: PH due to lung diseases and/or hypoxia; group 4: PH due to pulmonary artery obstructions; group 5: PH with unclear and/or multifactorial mechanisms.