Updated classification of drugs and toxins associated with PAH
| Definite | Possible |
| Aminorex | Cocaine |
| Fenfluramine | Phenylpropanolamine |
| Dexfenfluramine | l-tryptophan |
| Benfluorex | St John's wort |
| Methamphetamines | Amphetamines |
| Dasatinib | Interferon-α and -β |
| Toxic rapeseed oil | Alkylating agents |
| Bosutinib | |
| Direct-acting antiviral agents against hepatitis C virus | |
| Leflunomide | |
| Indirubin (Chinese herb Qing-Dai) |