TABLE 2

Persistent pulmonary hypertension of the newborn (PPHN) and associated disorders

Idiopathic PPHNMyocardial dysfunction (asphyxia, infection)
Down syndromeStructural cardiac diseases
Meconium aspiration syndromeHepatic and cerebral arteriovenous malformations
Respiratory distress syndrome
Transient tachypnoea of the newbornAssociations with other diseases:
Pneumonia/sepsis Placental dysfunction (pre-eclampsia, chorioamnionitis, maternal hypertension)
Developmental lung disease Metabolic disease
Peri-natal stress Maternal drug use or smoking