TABLE 2

Prospective change in forced expiratory volume in 1 s (FEV₁) and diffusing capacity of the lung for carbon monoxide (D_LCO) and relationship to vitamin D binding protein (VTDB)

	UK cohort				NHLBI cohort
	Untreated	p-value^#	Rapamycin	p-value^#	Untreated	p-value^#
Subjects n	64		27		136
ΔFEV₁ mL per year	−32.6±111.2	ns	24.3±141.4	ns	−94.7±96.2	ns
ΔD_LCO mmol·min⁻¹·kPa⁻¹ per year	−0.2±0.40	ns	−0.17±0.23	ns	−0.23±0.31	ns
VTDB µg·mL⁻¹	273±96		281±105		255±53.4

Data are presented as mean±sd, unless otherwise stated. NHLBI: National Heart, Lung and Blood Institute. ^#: p-value for Spearman's correlation with serum VTDB. ns: nonsignificant.