TABLE 2

Baseline characteristics of chronic thromboembolic pulmonary hypertension (CTEPH)-operated group versus patients who declined surgery (patient choice)

CTEPH-operatedDeclined surgery (patient choice)p-value
Subjects n27272
Age years58±1468±16<0.001
Female45630.007
BMI kg·m−230±729±70.485
WHO FC I/II versus II/IV13/8717/830.462
Duration of symptoms0.009
 <1 year1422
 1–2 years4038
 2–5 years2717
 >5 years1611
 Not clear313
ISWD m232±185169±1770.009
RAP mmHg11±512±60.192
mPAP mmHg47±1146±100.360
Cardiac index L·min−1·m−22.5±0.82.6±0.80.305
PCWP mmHg12±412±50.667
PVR WU7.7±48±40.767
SvO2 %61±861±90.610
FEV1 % pred83±4382±210.714
FVC % pred95±2196±230.702
DLCO % pred65±1561±170.084
History of VTE74690.489
History of cancer660.827
Smoking38350.664
Obesity39260.048
CAD1180.620
LV dysfunction260.131
CKD314<0.001
COPD13170.356
PH therapy following diagnosis74750.849

Data are presented as mean±sd or %, unless otherwise stated. BMI: body mass index; WHO FC: World Health Organization Functional Class; ISWD: incremental shuttle walk distance; RAP: right atrial pressure; mPAP: mean pulmonary arterial pressure; PCWP: pulmonary capillary wedge pressure; PVR: pulmonary vascular resistance; WU: Wood units; SvO2: mixed venous oxygen saturation; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; VTE: venous thromboembolism; CAD: coronary artery disease; LV: left ventricular; CKD: chronic kidney disease; COPD: chronic obstructive pulmonary disease; PH: pulmonary hypertension. Comparisons between continuous variables and categorical variables were made by the t-test and the Chi-squared test, respectively.