Longitudinal tidal-breathing nasal nitric oxide (NO) measurements scheduled at <2 weeks and at 4, 8, 12, 18 and 24 months of age in 44 included healthy infants
Characteristics | Results | |||||
Subjects n | 44 | 39 | 31 | 21 | 12 | 16 |
Intended age at measurement | <8 days | 4 months | 8 months | 12 months | 18 months | 24 months |
Actual age at measurement | 1–14 days | 3.6–6.3 months | 7.6–9.8 months | 10.4–14.2 months | 15.2–21.0 months | 22.2–27.1 months |
Tidal-breathing nasal NO# ppb | 46 (29–69) | 98 (56–130) | 129 (60–200) | 171 (110–228) | 178 (137–261) | 283 (203–389) |
Tidal-breathing nasal NO# nL·min−1 | 15 (9.6–22.8) | 32 (18.5–42.9) | 42.6 (19.8–66) | 56.4 (36.3–75.2) | 58.7 (45.2–86.1) | 93.4 (67.0–128.4) |
Adherence to scheduled measurements % | 100 | 88.6 | 70.5 | 47.7 | 27.3 | 36.4 |
Data is presented as median (IQR) unless otherwise stated. #: sampling flow rate was 0.33 L·min−1 (conversion: nasal NO (ppb)×flowrate (L·min−1)=nasal NO (nL·min−1)).