Subjects n | FEV1 mL Difference (95% CI)# | FVC mL Difference (95% CI)# | FEV1/FVC % Difference (95% CI)# | |
Maternal smoking during pregnancy | ||||
No | 2040 | Reference | Reference | Reference |
Yes | 254 | −32.7 (−91.9 to −26.4) | 16.1 (−54.0 to −86.2) | −1.1 (−2.0 to −0.2) |
SHS exposure during infancy | ||||
No | 1833 | Reference | Reference | Reference |
Yes | 447 | −2.4 (−49.6 to −44.8) | 20.2 (−35.0 to −75.4) | −0.6 (−1.3 to −0.1) |
SHS exposure at 16 years | ||||
No | 1911 | Reference | Reference | Reference |
Yes | 271 | 35.1 (−22.7 to −92.8) | 65.0 (−3.9 to −133.9) | −0.7 (−1.5 to −0.2) |
Participant's smoking | ||||
Nonsmokers | 2015 | Reference | Reference | Reference |
Adolescent smoking¶ | 280 | −12.6 (−69.3 to −44.2) | 16.6 (−50.1 to −83.3) | −0.9 (−1.8 to −0.1) |
Occasional smokers | 178 | −34.4 (−103.6 to −34.8) | 17.2 (−64.1 to −98.4) | −1.1 (−2.1 to −0.04) |
Daily smokers | 102 | 26.3 (−64.3 to 116.9) | 15.6 (−91.2 to 122.3) | −0.7 (−2.1 to 0.6) |
FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; SHS: secondhand smoke. #: calculated by linear regression on the mean adjusted for sex, age and height; ¶: daily or occasional smoking.