Author | Year | Patients n | Prevalence % | Sensitivity | Specificity | PPV | NPV | Lymph node reached |
VATS | ||||||||
Cerfolio [90] | 2007 | 39 | 92 | 1 | 1 | 1 | 1 | Left side: 5, 6, 7, 8L, 9L Right side: 4R, 7, 8L, 9L |
Massone [91] | 2003 | 55 | 55 | 1 | 1 | 1 | 1 | |
Sebastian-Quetlas [92] | 2003 | 79 | 24 | 0.58 | 1 | 1 | 0.88 | |
VAM | ||||||||
Declauwé [68]¶ | 2017 | 105 | 26 | 0.73 | 1 | 1 | 0.92 | 2R, 2L, 4R, 4L, 7, 8R, 8L |
Wei [101] | 2014 | 1240# | 46 | 0.90 | 1 | 1 | 0.92 | |
Sayar [102] | 2011 | 104 | 29 | 0.90 | 1 | 1 | 0.96 | |
Anraku [103] | 2010 | 89 | 22 | 0.95 | 1 | 1 | 0.99 | |
Leschber [104] | 2008 | 119 | 17 | NA | 1 | NA | 0.83 | |
Kimura [105] | 2007 | 209 | 31 | 0.78 | 1 | 1 | 0.91 | |
Lardinois [75] | 2003 | 195 | 34 | 0.87 | 1 | 1 | 0.92 | |
Venissac [106] | 2003 | 154 | 71 | 0.97 | 1 | 1 | 0.94 | |
ECM | ||||||||
Witte [107] | 2013 | 92 | 21 | 0.94 | 1 | 1 | 0.96 | 5, 6 |
Obiols [108] | 2012 | 221 | 15 | 0.68 | 1 | 1 | 0.94 | |
Metin [109] | 2011 | 55 | 24 | 0.69 | 1 | 1 | 0.89 | |
Freixinet [110] | 2000 | 93 | 34 | 0.81 | 1 | 1 | 0.91 | |
Ginsberg [111] | 1987 | 100 | 29 | 0.71 | 1 | 1 | 0.89 |
PPV: positive predictive value; NPV: negative predictive value; NA: not available. #: the authors report 997 conventional mediastinoscopies and 243 VAM. Staging values were calculated based on the total number. ¶: study in the context of clinical N1 disease.