TABLE 1

Baseline characteristics of the INPUT cohort

Subjects508
Demographic data
 Age at baseline years61.2±16.2
 Sex
  Male271 (53.3)
  Female237 (46.7)
 BMI kg·m-228±5.4
 Smoking status
  Current smoker90 (17.7)
  Ex-smoker115 (22.6)
  Nonsmoker303 (59.6)
Pulmonary embolism management 
 Thrombolysis25 (4.9)
 Surgery0 (0)
 Long-term anticoagulation
  Oral anticoagulation485 (95.5)
  LWMH9 (1.8)
  Heparin11 (2.2)
  Unknown3 (0.6)
Thromboembolic risk factors and history 
 Unprovoked pulmonary embolism227 (44.7)
 Previous history of pulmonary embolism71 (14.0)
 Concomitant DVT at diagnosis176 (34.6)
 Previous history of DVT74 (14.6)
 Family history of DVT or pulmonary embolism73 (14.4)
 Thrombophilic disorders25 (4.9)
 Antiphospholipid antibodies4 (0.8)
 Major surgery setting83 (16.3)
 Trauma (major trauma, fractures)36 (7.1)
 Immobility (hospital and nonhospital setting)143 (28.1)
 Hormonal (HRT, pregnancy, oral contraception)68 (13.4)
Medical history 
 History of malignancy56 (11.0)
 Active malignancy27 (5.3)
 Rheumatoid arthritis10 (2.0)
 Inflammatory bowel disease8 (1.6)
 Splenectomy3 (0.6)
 Pacemaker/VA shunt5 (1.0)
 Infection of pacemaker or VA shunt2 (0.4)
 Congestive heart failure3 (0.6)
 Cerebrovascular disease20 (3.9)

Data are presented as n, mean±sd or n (%). BMI: body mass index; LWMH: low-weight molecular heparin; DVT: deep vein thrombosis; HRT: hormone replacement therapy; VA: ventriculoatrial.