TABLE 5

The relationship between baseline haemodynamic parameters and incident COPD stratified according to CAD

Sample size±eventsHR per 10 mmHg or bpm (95% CI)p-value
No CAD
 ΔSBP in all19 579±10941.106 (1.016–1.204)0.020
 ΔSBP in smokers8471±8611.118 (1.017–1.229)0.021
 RHR all19 526±10861.063 (0.996–1.134)0.064
 RHR smokers8443±8531.097 (1.020–1.179)0.013
CAD
 ΔSBP in all5068±4701.081 (0.957–1.221)0.209
 ΔSBP in smokers2787±3631.102 (0.959–1.267)0.169
 RHR in all5056±4701.086 (0.983–1.199)0.105
 RHR in smokers2779±3631.149 (1.026–1.285)0.016

All analyses adjusted for age, sex, body mass index, diabetes, total cholesterol, supine SBP, antihypertensive therapy, and forced vital capacity and forced expiratory volume in 1 s expressed as a percentage of predicted values. HR: hazard ratio; CAD: coronary artery disease; bpm: beats per min; ΔSBP: orthostatic systolic blood pressure decrease; RHR: resting heart rate.