First trimester CRL z-score | Second trimester BPD z-score | Second trimester femur length z-score | |

Asthma | |||

Asthma prescriptions | −0.186±1.06 (n=111) | −0.002±1.00 (n=146) | −0.081±1.03 (n=145) |

No asthma prescriptions | 0.024±0.99 (n=954) | −0.008±0.98 (n=1320) | 0.013±0.97 (n=1315) |

OR^{#} (95% CI) for asthma (for 1 sd decrease in z-score) | 1.26 (1.03–1.54)^{¶} | 0.99 (0.83–1.19) | 1.10 (0.92–1.32) |

Eczema | |||

Eczema prescriptions | 0.011±0.92 (n=85) | 0.054±1.03 (n=111) | 0.044±1.17 (n=111) |

No eczema prescriptions | 0.002±1.00 (n=980) | −0.013±0.98 (n=1355) | 0.0008±0.96 (n=1349) |

OR^{#} (95% CI) for eczema (for 1 sd decrease in z-score) | 1.01 (0.81–1.27) | 0.93 (0.76–1.14) | 0.96 (0.78–1.17) |

Data are presented as mean±sd, unless otherwise stated. Gestation and sex were included in the calculation of z-scores, but not included in the logistic model. CRL: crown–rump length; BPD: biparietal diameter. ^{#}: logistic regression adjusted for maternal smoking during pregnancy and maternal history of asthma; ^{¶}: p=0.027.