Treatment compliance and duration#
| Ciprofloxacin DPI 14 days on/off | Placebo 14 days on/off | Ciprofloxacin DPI 28 days on/off | Placebo 28 days on/off | |
| Patients n | 137 | 68 | 141 | 70 |
| Compliance % | ||||
| Mean±sd | 94.4±8.4 | 91.8±10.3 | 94.3±10.1 | 89.9±15.8 |
| Compliance ≥80% n (%) | 129 (94.2) | 60 (88.2) | 129 (91.5) | 60 (85.7) |
| Treatment duration days | ||||
| Mean±sd | 262.4±105.9 | 252.2±112.1 | 266.0±89.7 | 234.6±110.8 |
| Median | 322.0 | 322.0 | 308.0 | 307.0 |
DPI: dry powder for inhalation. #: compliance was determined after imputation of (partially) missing exposure dates as number of capsules taken/number of planned capsules. Treatment duration was assessed from first to last day of study drug intake irrespective of interruptions or off-cycles; the final off-cycle after the last dose was not included. The maximum treatment duration was 322 days for the 14-day on/off arm and 308 days for the 28-day on/off arm.