TABLE 3

Spearman's correlations for selected parameters with the change in dyspnoea intensity ratings at iso-time with hyperoxia versus room air

r-valuep-value
ΔEET min−0.670.02
FVC % pred−0.430.18
DLCO % pred−0.110.75
Peak incremental VO2 % pred0.110.75
ΔSpO2 at iso-time %−0.040.91
ΔSpO2 at peak exercise %−0.060.86
ΔVE at iso-time L·min−10.140.68
ΔVT at iso-time L−0.460.16
ΔFB at iso-time breaths·min−10.230.50
ΔEELV at iso-time % TLC0.370.26
ΔEILV at iso-time % TLC0.270.43
ΔEMGdi at iso-time %max0.410.21
ΔNMU at iso-time EMGdi (%max): VT (% VC)0.630.04

Δ: difference between selected parameter with hyperoxia versus room air; EET: exercise endurance time; FVC: forced vital capacity; DLCO: diffusing capacity of the lungs for carbon monoxide; V′O2: oxygen consumption; SpO2: arterial oxygen saturation measured by pulse oximetry; VE: minute ventilation; VT: tidal volume; FB: breathing frequency; EELV: end-expiratory lung volume; TLC: total lung capacity; EILV: end-inspiratory lung volume; EMGdi: electromyography of the crural diaphragm; NMU: neuromechanical uncoupling; VC: vital capacity.