Characteristics | Subjects# | z-score | p-value¶ |
Sex | 0.072 | ||
Male | 774 | −0.22 (−0.30 to −0.13) | |
Female | 827 | −0.32 (−0.40 to −0.24) | |
Age group years+ | <0.001 | ||
0–9 | 683 | −0.27 (−0.33 to −0.21) | |
10–19 | 683 | −0.31 (−0.37 to −0.25) | |
20–29 | 199 | −0.22 (−0.29 to −0.14) | |
30–39 | 119 | −0.20 (−0.29 to −0.11) | |
40–49 | 89 | −0.22 (−0.32 to −0.12) | |
>50 | 79 | −0.23 (−0.35 to −0.11) | |
Country§ | <0.001 | ||
Australia | 55 | −0.31 (−0.60 to −0.01) | |
Belgium | 79 | −0.66 (−0.92 to −0.40) | |
Cyprus | 30 | −0.14 (−0.53 to 0.26) | |
Denmark | 91 | −0.36 (−0.59 to −0.14) | |
France | 119 | 0.18 (−0.03 to 0.39) | |
Germany | 94 | −0.76 (−0.99 to −0.53) | |
Israel | 142 | −0.50 (−0.70 to −0.31) | |
Italy | 38 | −0.41 (−0.77 to −0.06) | |
Netherlands | 66 | −0.18 (−0.45 to 0.09) | |
Norway | 22 | −0.64 (−1.10 to −0.17) | |
Poland | 97 | −0.22 (−0.46 to 0.02) | |
Switzerland | 47 | −0.01 (−0.32 to 0.29) | |
Turkey | 30 | −1.09 (−1.51 to −0.66) | |
UK | 277 | −0.15 (−0.29 to −0.01) | |
USA/Canada | 414 | −0.16 (−0.30 to −0.05) | |
Diagnostic certainty | 0.897 | ||
Definite PCD diagnosisƒ | 1054 | −0.28 (−0.35 to −0.21) | |
Probable PCD diagnosis## | 254 | −0.27 (−0.42 to −0.12) | |
Clinical diagnosis only | 293 | −0.24 (−0.37 to −0.10) |
Data is presented as n or mean (95% CI) unless otherwise stated. Mean z-scores and 95% CI for each group were derived after adjusting for the remaining characteristics. #: total number of subjects (N) was 1601. ¶: likelihood ratio test p-value indicating whether the characteristic explains differences in height within the study population. +: age at measurement (numbers represent the unique number of patients in each group, however, patients can be included in more than one group). §: patients from Serbia were excluded from this analysis because no national references were available. ƒ: defined as hallmark PCD electron microscopy findings and/or biallelic gene mutation, identified based on the ERS PCD Diagnostics Task Force guidelines. ##: abnormal light or high frequency video microscopy finding and/or low nasal NO value.