TABLE 1

Baseline patient characteristics

CharacteristicCategory
HCAExARDBLDLCMPMp-value
Subjects525941705652
Gender<0.001
 Male34 (65)58 (98)40 (98)47 (67)37 (66)43 (83)
 Female18 (35)1 (2)1 (2)23 (33)19 (34)9 (17)
Age years51.2 (34.5–56.7)53.2 (50.2–55.3)58.3 (55.3–62.2)58.8 (40.6–68.0)69.9 (64.3–72.7)67.3 (61.6–72.9)<0.001
Weight kg78.3±17.185.6±11.484.5±14.671.3±15.170.7±14.474.5±10.3<0.001
Length m1.76±0.091.77±0.061.74±0.051.71±0.091.68±0.081.72±0.08<0.001
BMI kg·m−225.2 (22.2–27.7)26.9 (24.9–28.9)26.8 (24.5–31.5)24.4 (20.8–25.9)24.0 (21.6–27.8)25.4 (23.6–27.2)<0.001
Smoking status<0.001
 Never smoked35 (67)19 (32)15 (37)24 (35)6 (10)19 (37)
 Current smoker1 (2)14 (24)8 (20)14 (20)25 (45)5 (9)
 Ex-smoker16 (31)26 (44)18 (43)31 (45)25 (45)28 (54)
Smoking duration pack-years0.0 (0.0–1.61)6.0 (0.0–21.5)5.3 (0.0–24.8)7.5 (0.0–36.0)30.0 (14.4–45.0)2.65 (0.0–14.7)<0.001
Subgroups
 Lung embolism3
 COPD28
 Fibrous tumour1
 Allergy1
 Cystic fibrosis15
 Asthma6
 Pneumonia10
 Emphysema3
 Pleuritis1
 Pulmonary hypertension1
 Granulomatosis with polyangiitis1
 Epithelioid36
 Sarcomatoid3
 Biphasic/mixed3
 Unknown10

Data are presented as n, n (%), median (Q1–Q3) or mean±sd unless otherwise stated. BMI: body mass index; COPD: chronic obstructive pulmonary disease; AEx: asymptomatic former asbestos-exposed individual; ARD: patients with benign asbestos-related diseases; BLD: patients with benign non-asbestos-related lung diseases; HC: healthy controls; LC: patients with primary lung cancer; MPM: patients with malignant pleural mesothelioma.