TABLE 2

Relationships between assessments of cardiovascular risk and BSI/selected individual components

PWV m·s−1Troponin μg·L−1NT-proBNP pmol·L−1Fibrinogen g·L−1CRP mg·L−1
r/ρp-valuer/ρp-valuer/ρp-valuer/ρp-valuer/ρp-value
Subjects n1019897100100
BSI0.45<0.001#0.52<0.001#0.340.001#0.390.001#0.240.017
Age0.77<0.001#0.59<0.001#0.47<0.001#0.280.0120.100.323
Annual exacerbation
frequency
 ≥3 events·year-1 (n=40)10.5±2.70.0110.008 (0.004–0.013)0.04711.0 (5.0–18.5)0.2933.5 (2.7–4.3)0.2534.8 (2.0–11.8)0.005
 <3 events·year-1 (n=61)9.2±1.70.005 (0.003–0.008)9.0 (3.0–17.0)3.2 (2.7–3.9)2.2 (0.5–5.4)
FEV1 L−0.340.001#−0.42<0.001#−0.340.001#−0.53<0.001#−0.45<0.001#
FEV1 % predicted0.020.832−0.280.006−0.110.301−0.43<0.001#−0.340.001#
CT lobes involved0.140.1590.170.0910.240.020.070.5700.070.482

Data are presented as mean±sd or median (interquartile range), unless otherwise stated. Significant findings are presented in bold. BSI: bronchiectasis severity index; PWV: pulse-wave velocity; NT-proBNP: N-terminal pro-brain natriuretic peptide; CRP: C-reactive protein; FEV1: forced expiratory volume in 1 s; CT: computed tomography. #: significant after Hochberg adjustment for multiple comparisons; : significant at α<0.05.