TABLE 3

Proportion of newborn screened cystic fibrosis infants with “normal” or “abnormal” results on each test occasion, and on more than one test occasion

3 months1 year2 years3 months and 1 year3 months and 2 years1 year and 2 yearsAll test occasions
Total LCI57596154565853
Normal LCI48 (84)49 (83)52 (85)41 (76)39 (70)41 (71)34 (64)
Abnormal LCI9 (16)10 (17)9 (15)5 (9)1 (2)2 (3)0 (0)
Total FRCpleth50595747475444
Normal FRCpleth41 (82)49 (83)46 (81)35 (74)31 (66)38 (70)27 (61)
Abnormal FRCpleth9 (18)10 (17)11 (19)4 (9)4 (9)3 (6)2 (5)
Total FEV0.559585656535452
Normal FEV0.551 (86)54 (93)52 (93)46 (82)43 (81)46 (85)39 (75)
Abnormal FEV0.58 (14)4 (7)4 (7)1 (2)0 (0)0 (0)0 (0)
Total results from all#47575444415139
All normal#27 (57)36 (63)35 (65)23 (52)14 (34)20 (39)12 (31)
All abnormal#0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)

Data are presented as n or n (%). LCI: lung clearance index; FRCpleth: plethysmographic functional residual capacity; FEV0.5: forced expiratory volume in 0.5 s. #: “all” represents LCI, FRCpleth and FEV0.5; “abnormal” and “normal” defined on basis of 1.96 z-score threshold for LCI and FRCpleth and −1.96 for FEV0.5.