Model-based estimates for 30-day mortality in reference to categories of admission glucose levels
Non-fasting AGL mmol·L−1 | Patients | Ref. value | Bivariate analysis (Model A) | Adjusted for PSI score (Model B) | Adjusted for CURB-65 score (Model C) | |
At risk n | Died n (%) | |||||
4–<6 | 317 | 22 (6.9) | 5 | 2.15 (1.42–3.24) | 1.94 (1.25–3.02) | 2.07 (1.34–3.19) |
6–<8 | 733 | 38 (5.2) | 7 | Ref. | ||
8–<10 | 277 | 10 (3.6) | 9 | 1.29 (1.09–1.54) | 1.08 (0.91–1.27) | 1.10 (0.94–1.29) |
10–<12 | 98 | 8 (8.2) | 11 | 1.84 (1.33–2.54) | 1.33 (0.97–1.81) | 1.40 (1.04–1.90) |
12–<14 | 52 | 5 (9.6) | 13 | 2.49 (1.60–3.88) | 1.66 (1.06–2.59) | 1.81 (1.18–2.78) |
≥14 | 72 | 12 (16.7) | 15 | 3.19 (1.86–5.45) | 2.03 (1.15–3.56) | 2.28 (1.32–3.93) |
Data in the first two columns are from a single imputation dataset. Model-based estimates of ORs (95% CIs) for 30-day mortality for several admission glucose level (AGL) categories. ORs were calculated for reference (Ref.) values in the centre of categories. Model A is for a second-degree polynomial fit of AGL only. Models B and C are the adjusted models with pneumonia severity index (PSI) and CURB-65 scores (confusion, urea >7 mmol·L−1, respiratory rate ≥30 breaths·min−1, blood pressure <90 mmHg (systolic) or ≤60 mmHg (diastolic), age ≥65 years), respectively. Formulas for the final logistic regression models, in which x denotes admission glucose level, β denotes model betas for CURB-65 categories, and z denotes PSI score, were as follows. Model A: . Model B:
. Model C:
. Model C betas were 0.92(CURB 65 score 1), 1.63(CURB 65 score 2), 2.42(CURB 65 score 3), 1.88(CURB 65 score 4) and 3.17(CURB 65 score 5).