Univariate analysis relating survival time to selected baseline variables

Hazard ratio (95% CI)p-value
Sex (female)1.017 (0.573–1.806)0.954
Age1.004 (0.977–1.031)0.794
WHO/NYHA functional class IV2.010 (1.052–3.840)0.034
6MWD0.995 (0.993–0.997)<0.001
RAP0.930 (0.861–1.005)0.066
mPAP0.997 (0.968–1.027)0.834
Cardiac index1.401 (0.994–1.976)0.054
PVR0.966 (0.898–1.039)0.350
FVC0.984 (0.969–0.999)0.042
KCO0.982 (0.968–0.996)0.013
Radiological stage IV1.845 (0.954–3.559)0.069
PAH-targeted therapy0.845 (0.526–2.650)0.684

WHO: World Health Organization; NYHA: New York Heart Association; 6MWD: 6-min walk distance; RAP: right atrial pressure; mPAP: mean pulmonary artery pressure; PVR: pulmonary vascular resistance; FVC: forced vital capacity; KCO: transfer coefficient of the lung for carbon monoxide; PAH: pulmonary arterial hypertension.