TABLE 6

Genotyping results of paired clinical isolates from patients with recurrent Mycobacterium avium complex (MAC) lung disease#

TotalReinfectionRelapsep-value
Subjects27 (100)20 (74)7 (26)
Type of disease0.091
 NB22 (81)18 (82)4 (18)
 Noncavitary NB17143
 Cavitary NB541
 Fibrocavitary form5 (19)2 (40)3 (60)
Aetiology0.091
 M. avium12 (44)11 (92)1 (8)
 M. intracellulare15 (56)9 (60)6 (40)
Time interval between treatment completion and recurrence months10.6 (5.5–18.3)13.0 (6.0–23.7)6.0 (4.8–8.5)0.040

Data are presented as n (%), n or median (interquartile range), unless otherwise stated. NB: nodular bronchiectatic form. #: “recurrent MAC lung disease” only includes cases where MAC lung disease redeveloped due to the same species; : repetitive sequence-based PCR profiles indicated that genotypes differed from the original isolates (reinfection) or were identical to the initial genotype (relapse).