TABLE 1

Characteristics of the five multidrug-resistant tuberculosis clusters#

Patient numberIdentification methodCountry of birthDisease typeGenotypingMIRU-VNTR
katG315inhArpoBgyrAgyrBpncarrsembB
1Contact tracingGeorgiaPulmonaryS315TSS531LD94HSSSM306V244 223 352 644 425 173 353 623
2Contact tracingGeorgiaPulmonary and genitalS315TSS531LD94HSSSM306V244 223 352 644
425 173 353 623
3Contact tracingAlgeriaPulmonaryS315T−15c>tH526DSE540VT100PSM306I223 234 242 434
425 143 323 732
4Contact tracingAlgeriaPulmonaryS315T−15c>tH526DSE540VT100PSM306I223 234 242 434
425 143 323 732
5Contact tracingAlgeriaPulmonaryS315TSS531LSSV139MSM306V334 323 312 244
225 153 333 622
6Contact tracingAlgeriaPulmonaryS315TSS531LSSV139MSM306V334 323 312 244
225 153 333 622
7GenotypingSudanPulmonaryS315TSS531LSSV139MSM306V334 323 312 244
225 153 333 622
8GenotypingChinaPleuralS315TSS531LSSG97DSS222 213 222 234
225 153 333 622
9GenotypingRomaniaPulmonaryS315TSS531LSSG97DSS222 213 222 234
225 153 333 622
10GenotypingRomaniaPleuralS315T−15c>tS531LSSSSS235 237 232 244
425 113 323 632
11GenotypingUkrainePulmonaryS315T−15c>tS531LSSSSS235 237 232 244
425 113 323 632

#: index case is presented on the first line for each cluster; : by Centre de Lutte Anti-Tuberculeuse de Paris (CLAT75). MIRU-VNTR: mycobacterial interspersed repetitive-unit variable-number tandem repeat.